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The Double Non-Helix By Ken Biegeleisen, M.D., Ph.D. |
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W-C helical structure in de-proteinized crystals. |
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DNA structure in living systems: non-helical! |
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If you can patiently work your way through these presentations, you will come to realize that the Watson-Crick double-helix structure may be mainly an artifact of deproteinization and crystallization. (Working scientists: If you regularly perform agarose gel electrophoresis of DNA, click here to learn how you can get involved in the process of establishing the role of non-helical DNA structure in living systems.) |
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To download the virtual structure files in this presentation (PDB accession #'s 2AWR, 2AWS): |
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Read the published manuscripts:
"Probable Structure of the Protamine-DNA Complex" (Journal of Theoretical Biology)
"Topologically non-linked circular duplex DNA" (Bulletin of Mathematical Biology)
Contact:
Ken Biegeleisen, M.D., Ph.D.
19 East 80 Street, Suite 1E
New York, N.Y. 10075
United States of America
Tel: (212) 717-4422
kb@NotAHelix.com.